王红声

发布部门:生物与医学工程学院 发布时间:2022-06-29

 

个人简介

上海交通大学分子生物学博士,阿德莱德大学博士后访问学者,现任东华大学生物与医学工程学院副研究员,硕士生导师。系中国医药教育协会生物材料专委会委员、中国微米纳米技术学会高级会员、中国生物医学工程学会会员。

 

研究方向

1. 新型经皮给药(免疫)系统的构建及应用研究

2. 生物材料与组织再生相关研究

 

荣誉及获奖情况

荣获2015年度上海市自然科学三等奖(第三完成人)。

 

主持与承担主要项目情况

主持或参与多项国家及上海市科研项目,包括国家自然科学基金、国家重点研发专项计划、上海市国际合作项目、上海市自然基金等。

 

发表论著情况

迄今累计发表学术论文80余篇,其中以第一作者或通讯作者在Journal of Controlled Release, ActaBiomaterialia, Composites Part B, Materials and Design, Nanomedicine 等国际知名期刊发表学术论文20余篇。

 

主要学术论文

1.        Di Jiang, Yuxin Jiang, Kaili Wang, Zhe Wang, Yifei Pei, Jinglei Wu, Chuanglong He, Xiumei Mo, Hongsheng Wang*. Binary ethosomes-based transdermal patches assisted by metal microneedles significantly improve the bioavailability of carvedilol. Journal of Drug Delivery Science and Technology, 2022, 74: 103498.

2.        Kaili Wang, Xiaoyun Wang, Di Jiang, Yifei Pei, Zhe Wang, Xiaojun Zhou, Jinlei Wu, Xiumei Mo, Hongsheng Wang*. Delivery of mRNA vaccines through non-invasive transcutaneous route effectively inhibits tumor growth. Composites Part B: Engineering, 2022, 233: 109648.

3.        Xinran Song, Yuxin Jiang, Weixing Zhang, Gomaa Elfawal, Kaili Wang, Di Jiang, Huoyan Hong, Jinglei Wu, Chuanglong He, Xiumei Mo, Hongsheng Wang*. Transcutaneous Tumor Vaccination Combined With aPD-1 Treatment Produces a Synergistic Antitumor Effect. Acta Biomaterialia. 2022, 140: 247-260.

4.        Huoyan Hong, Xiaoyun Wang, Xinran Song, Gomaa El Fawal, Kaili Wang, Jiang Di, Yifei Pei, Zhe Wang, Hongsheng Wang*. Transdermal delivery of interleukin-12 gene targeting dendritic cells enhances the anti-tumour effect of programmed cell death protein 1 monoclonal antibody. Biomater Transl. 2021, 2(2): 151-164.

5.        HONG Huoyan, ZHANG Dongdong, LIN Si, HAN Feng, WANG Kaili, JIANG Di, WU Jinglei, MO Xiumei and WANG Hongsheng*. Green Electrospun Silk Fibroin Nanofibers Loaded with Cationic Ethosomes for Transdermal Drug Delivery.Chem. Res. Chinese Universities, 2021, 37(3): 488-495.

6.        Xingxing Yang, Xiaoyun Wang, Huoyan Hong, Gomaa Elfawal, Si Lin, Jinglei Wu, Yuxin Jiang, Chuanglong He, Xiumei Mo, Guoyin Kai, Hongsheng Wang*. Galactosylated chitosan-modified ethosomes combined with silk fibroin nanofibers is useful in transcutaneous immunization. Journal of Controlled Release., 2020, 327: 88-99.

7.        Gomaa F. El Fawal, Huoyan Hong, Xinran Song, Jinglei Wu, Meiqi Sun; Lin Zhang, Chuanglong He, Xiumei Mo, Hongsheng Wang*. Polyvinylalcohol/hydroxyethylcellulose containing ethosomes as a carrier for transdermal drug delivery applications. Applied Biochemistry and Biotechnology. 2020, 191, 1624-1637.

8.        Gomaa El Fawal, Huoyan Hong, Xinran Song, Jinglei Wu, Meiqi Sun, Chuanglong He, Xiumei Mo, Yuxin Jiang, Hongsheng Wang*. Fabrication of antimicrobial films based on hydroxyethylcellulose and ZnO for food packaging application. Food Packaging and Shelf Life, 2020, 23, 100462.

9.        Ma L, Wang X, Wu J, Zhang D, Zhang L, Song X, Hong H, He C, Mo X, Wu S*, Kai G*Wang H*. Polyethylenimine and sodium cholate-modified ethosomes complex as multidrug carrier for the treatment of melanoma through transdermal delivery. Nanomedicine (Lond). 2019, 14(18): 2395-2408.

10.    Dongdong Zhang, Linpeng Fan, Linlin Ma, Junqiu Liu, Kai Zhou, Xinran Song, Meiqi Sun, Xiumei Mo,Chuanglong He, Yuxin Chen, and Hongsheng Wang*. Helicobacter pylori Ribosomal Protein-A2 Peptide/Silk Fibroin Nanofibrous Composites as Potential Wound Dressing. J. Biomed. Nanotechnol., 2019, 15: 507-517.

11.    Linlin Ma, Dongdong Zhang, Xingxing Yang, Lin Zhang, Jin Chu, Guoyin Kai, Chuanglong He, Xiumei Mo and Hongsheng Wang*. Cirsium Japonicum DC ingredients-loaded silk fibroin nanofibrous matrices with excellent hemostatic activity. Biomed. Phys. Eng. Express, 2018, 4(2): 025035.

12.    Linpeng Fan, Zengxiao Cai, Xiaohua Geng, Hongsheng WANG*,JingliangLi, Chuanglong He, Xiumei Mo, Xungai Wang. Fabrication and characterization of compound vitamin B/silk fibroin nanofibrous matrices. Journal of Controlled Release., 2017, 259: e85-e86.

13.    Xingxing Yang, Linpeng Fan, Linlin MA, Yunyi Wang, Si LinFan Yu, Xiaohan Pan, Gejie Luo, Dongdong Zhang, WANG Hong-sheng*.Green electrospun Manuka honey/silk fibroin fibrous matrices as potential wound dressing. Materials & Design, 2017, 119: 76–84.

14.    Xingxing Yang, Xiaoyun Wang, Fan Yu, Linlin MaXiaohan Pan, Gejie Luo, Si LinXiumei Mo, Chuanglong He and Hongsheng Wang*. Hyaluronic acid/EDC/NHS- crosslinked green electrospun silk fibroin nanofibrous scaffolds for tissue engineering. RSC Advances, 2016, 6: 99720 - 99728.

15.    Si Lin, Mengxia Chen, Huayue Jiang, Linpeng Fan, Binbin Sun, Fan Yu, Xingxing Yang, Xiangxin Lou, Chuanglong He, Hongsheng Wang*. Green electrospun grape seed extract-loaded silk fibroin nanofibrousmats with excellent cytocompatibility and antioxidant effect. Colloids and Surfaces B: Biointerfaces, 2016, 139:156-163.

 

其他信息

获国家发明专利授权10余项(已许可转让1项):

1.王红声,宋新然,洪火炎,张东东,马琳琳. 一种利用静电喷雾法制备可靶向树突状细胞的载药醇质体微球的方法. 中国发明专利(ZL 2019 1 0701729.4),授权公告日20220318.

2.王红声,张东东,宋新然,洪火炎,马琳琳.一种双相经皮给药系统及其制备方法.中国发明专利(ZL 2019 1 0570830.0),授权公告日2021123.

3.王红声马琳琳,杨兴兴,张东东,余凡,潘潇涵,骆格杰.一种半乳糖化聚乙烯亚胺修饰的载药醇质体的制备方法.中国发明专利(ZL2017 1 0422572.2),授权公告日20210330.

4.王红声,杨兴兴,林思,余凡,马琳琳,骆格杰,潘潇涵.一种半乳糖化壳聚糖修饰的免疫醇质体的制备方法.中国发明专利(ZL2016 1 0172651.8),授权公告日20190806

5.王红声,余凡杨兴兴,林思,周晓菲,范林鹏.一种基于绿色电纺技术制备半乳糖壳聚糖-天然蛋白复合纳米纤维仿生支架的方法.中国发明专利(ZL2015 1 0990389.3),授权公告日20181023.

6.王红声,杨兴兴,林思,余凡. 一种提升丝素蛋白纳米纤维力学性能的处理方法,中国发明专利(ZL 2015 1 0256456.9.授权公告日20170503.

7.王红声,陈梦霞,冯炜,林思,何创龙,莫秀梅.一种负载护肤因子的鱼明胶-丝素蛋白复合纳米纤维膜的制备方法.中国发明专利(ZL2014 1 0211383.7),授权公告日20170329.

8.王红声,韩峰,崔呈俊,何创龙,莫秀梅.基于天然材料丝素蛋白和壳聚糖复合纳米纤维膜的制备.中国发明专利(ZL 2012 1 0473756.9),授权公告日20150121.

9.王红声,盛晓悦,范林鹏,何创龙,莫秀梅,崔呈俊,韩峰. 负载水溶性维生素E的丝素蛋白纳米纤维膜及其制备方法.中国发明专利(ZL 2012 1 0014530.2),授权公告日20140813.

10.王红声,崔呈俊,何创龙,莫秀梅.基于静电纺丝技术制备天然材料-脂质体复合纳米纤维,中国发明专利(ZL 2012 1 0273618.6.授权公告日20140226.

11.王红声,盛晓悦,范林鹏,何创龙,莫秀梅,崔呈俊,韩峰. 负载维生素AE的丝素蛋白纳米纤维膜及其制备方法.中国发明专利(ZL 2012 1 0014384.3),授权公告日20140129.

12.王红声,范林鹏,张葵花,何创龙,莫秀梅,刘君毅,蔡增晓. 具有护肤功效的丝素蛋白纳米纤维的制备方法.中国发明专利(ZL 2010 1 9063008.1),授权公告日201207042014328日独占许可转让.

 

联系方式

021-6779274218019062668whs@dhu.edu.cn