黄威

发布部门：生物与医学工程学院 发布时间：2024-06-12


个人简介

黄威，理学博士，中国科学院上海免疫与感染研究所研究员、课题组组长。2014年于中国科学院大学获得博士学位，2014年至2023年先后在美国罗格斯大学罗伯特医学院和约翰斯霍普金斯大学公共卫生学院进行博士后研究和担任副研究员。在Science、eLife、PLoS neglected tropical diseases、Philosophical Transactions of the Royal Society B、mBio等杂志发表论文20篇，引用次数1600余次。

研究方向

1.研究包括共生细菌和转基因蚊虫在内的蚊媒传染病的阻断策略;

2.研究蚊媒病原对于蚊虫、哺乳动物等宿主的侵染和宿主的防御机制;

3.研究针对蚊媒病原的高效疫苗和治疗药物；

4.研究控制蚊虫种群数量的生物防治策略。


荣誉及获奖情况

  1. 上海市白玉兰人才计划—2024年


主持与承担主要项目情况


发表论著情况


  1. Huang, W., Rodrigues, J., Bilgo, E., Tormo, J. R., Challenger, J. D., De Cozar-Gallardo, C., ... & Jacobs-Lorena, M. (2023). Delftia tsuruhatensis TC1 symbiont suppresses malaria transmission by anopheline mosquitoes. Science, 381(6657), 533-540. (IF= 63.82, 一区).

  2. Huang W., Vega-Rodriguez J., Kizito C., Jacbos-Lorena M. (2022). Combining transgenesis with paratransgenesis to fight malaria. elife, (IF=8.14, 生物学一区)

  3. Huang, W*., Fu, K., Gao, Q., Tejo, R. P., Floeter-Winter, L. M., & Gutierrez, A. P. (Eds.). (2022). Host-microbe interaction and coevolution. Frontiers Media SA (Editorial for Frontiers in Microbiologyand Frontiers in Genetics).

  4. Huang W, Cha S J, Jacobs‐Lorena M. New weapons to fight malaria transmission: A historical view. Entomological Research, 2022. (IF=1.358, 生物学三区)

  5. Huang W., Wang S., Jacbos-Lorena M. (2020). Self-limiting Paratransgenesis. PLOS Neglected Tropical Diseases (IF=4.411, 热带医学一区)

  6. Huang, W., Wang, S., & Jacobs-Lorena, M. (2020). Use of Microbiota to Fight Mosquito-Borne Disease. Frontiers in Genetics, 11. (IF=4.274, 生物学二区)

  7. Huang, W., Hong, S., Tang, G., Lu, Y., & Wang, C. (2019). Unveiling the function and regulation control of the DUF3129 family proteins in fungal infection of hosts. Philosophical Transactions of the Royal Society B, 374(1767), 20180321. (IF=6.237, 生物学一区).

  8. Huang, W., Liao, G., Baker, G. M., Wang, Y., Lau, R., Paderu, P., ... & Xue, C. (2016). Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in Cryptococcus neoformans. mBio, 7(3), e00478-16(IF=7.867, 生物学一区).

  9. Huang W., Shang Y. F., Chen P. L., Cen K., & Wang, C. S. (2015). Basic leucine zipper (bZIP) domain transcription factor MBZ1 regulates cell wall integrity, spore adherence, and virulence in Metarhizium robertsii. Journal of Biological Chemistry, 290(13), 8218-8231(IF=5.486, 生物学二区).

  10. Huang W., Shang Y. F., Chen P. L., Gao Q., Wang C. S. (2015). MrpacC regulates sporulation, insect cuticle penetration and immune evasion in Metarhizium robertsii.Environmental Microbiology, 17(4), 994-1008(IF=5.491, 生物学二区).

  11. Huang W., Zhang Y. H., Chen D. Q., Hu H. Q., Zhuang G. Q. (2009). Degradation and Remaining of the Bt Protein in Several Soils. Journal of Huazhong Agricultural University, 28(2): 169-173. (In Chinese)

其他发表论文

  1. Godoy, R. S. M., Barbosa, R. C., Huang, W., Secundino, N. F. C., Pimenta, P. F. P., Jacobs-Lorena, M., & Martins, G. F. (2023). The larval midgut of Anopheles, Aedes, and Toxorhynchites mosquitoes (Diptera, Culicidae): a comparative approach in morphophysiology and evolution. Cell and Tissue Research, 1-24. (IF= 4.06, 三区).

  2. Pascini, T. V., Jeong, Y. J., Huang, W., Pala, Z. R., Sá, J. M., Wells, M. B., ... & Vega-Rodríguez, J. (2022). Transgenic Anopheles mosquitoes expressing human PAI-1 impair malaria transmission. Nature communications, 13(1), 1-16.(IF=14.919, 生物学一区)

  3. Gao, H., Bai, L., Jiang, Y., Huang, W., Wang, L., Li, S., ... & Wang, S. (2021). A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipase. Nature Microbiology, 1-12. (IF=17.745, 生物学一区)

  4. Wang, S., Dos-Santos, A. L., Huang, W., Liu, K. C., Oshaghi, M. A., Wei, G., ... & Jacobs-Lorena, M. (2017). Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria. Science, 357(6358), 1399-1402. (IF= 63.82, 一区).

  5. Gao, Q., Lu, Y., Yao, H., Xu, Y. J., Huang, W., & Wang, C. S. (2016). Phospholipid homeostasis maintains cell polarity, development and virulence in Metarhizium robertsii. Environmental Microbiology, 18(11), 3976-3990(IF=5.491, 生物学二区).

  6. Duan Z.B., Chen Y. X., Huang W.,Shang Y. F., Chen P. L., Wang C. S. (2013). Linkage of autophagy to fungal development, lipid storage and virulence in Metarhizium robertsii. Autophagy, 9(4), 538-549(IF=16.061, 生物学一区).

  7. Gao Q*., Shang Y. F*., Huang W., Wang C. S. (2013). Glycerol-3-phosphate acyltransferase contributes to triacylglycerol biosynthesis, lipid droplet formation and host invasion in Metarhizium robertsii. Applied and Environmental Microbiology, 79, 7646-7653(IF=4.792, 生物学二区).

  8. Shang Y. F., Duan Z. B., Huang W., Gao Q., Wang C. S. (2012). Improving UV resistance and virulence of Beauveria bassiana by genetic engineering with an exogenous tyrosinase gene. Journal of Invertebrate Pathology, 109(1), 105-109(IF=2.841, 生物学二区).

  9. Gao Q., Jin K., Ying S. H., Zhang Y. J., Xiao G. H., Shang Y. F., Duan Z. B., Hu X., Xie X. Q., Zhou G., Peng G. X., Luo Z. B., Huang W., Wang B., Fang W. G., Wang S. B., Zhong Y., Ma L.J., St. Leger R. J., Zhao G. P., Pei Y., Feng M. G., Xia Y. X. and Wang C. S. (2011). Genome sequencing and comparative transcriptomics of the model entomopathogenic fungi Metarhizium anisopliae and M. acridum.PLoS Genetics, 7(1), e1001264

  10. Zhang Y. H., Huang W., Hu H. Q., Liu Y. R., Chen D. Q. (2007). Remaining Dynamics of Cry1Ab Proteins from Transgenic Bt Corn in Soils. Journal of Huazhong Agricultural University, 26(2), 485-490. (In Chinese)


联系方式

Email：whuang@siii.cas.cn 

办公地址：上海市徐汇区岳阳路320号新生命科学大楼B511