个人简介
张俊峰,麻醉学博士,上海交通大学医学院附属同仁医院麻醉手术科行政主任。2014年博士毕业于上海交通大学医学院。担任中国心胸血管麻醉分会舒适化医疗分会委员、中国抗癌协会肿瘤麻醉与镇痛专业委员会委员、中国医师协会麻醉学医师分会老年麻醉学组委员、中华医学会麻醉学分会超声学组委员、中国整形美容协会麻醉与镇静镇痛分会委员、中国超声医学工程学会麻醉与疼痛分会委员、上海市中医药学会围术期医学分会常务委员、上海医学会麻醉学分会委员(十一届)、上海医师协会麻醉科医师分会委员(第二届)、上海市医学会麻醉学分会心胸外科麻醉学组委员、上海市母婴安全专家库专家及第六届“长宁工匠”。主持国家自然科学基金面上项目、上海交通大学医工交叉面上和重点项目、上海市科委及上海市卫健委临床专项等科研课题7项;以第一作者/通讯作者在Anesthesiology、J Neuroinflammation、Neuropharmacology等杂志发表SCI论文20篇;参编当代麻醉学、现代麻醉学、区域麻醉解剖与实践等专著5部。
研究方向
术后认知功能障碍机制及围术期脑保护策略研究。
创伤性周围神经损伤后轴突导向再生机制及创新性生物材料开发应用研究。
荣誉及获奖情况
第六届“长宁工匠”
中国医院协会医院科技创新奖三等奖,超声在可视化麻醉和镇痛中的应用
美国麻醉医师协会(American Society of Anesthesiologists,ASA)年会,最佳基础研究论文一等奖(First prize of 2013 ASA best abstract for basic science)
国际华人麻醉学院(International Chinese Academy of Anesthesiology)年会,创意科学奖(Creative Science Award)
参与承担主要项目情况
国家自然基金面上项目,82372579,有氧运动通过Irisin激活αKG-TET2促进小胶质细胞抗炎效应改善老年术后认知功能障碍的机制研究,2024-01至2027-12,49万,在研,主持
上海交通大学医学院毕业后医学教育课程建设项目,BYH20250119,《床旁超声导向休克鉴别诊断的分层递进住院医师/专科医师培训课程》,2025-01至2025-12,3万,在研,主持
上海交通大学“交大之星”计划“医工交叉研究基金”重点项目,YG2024ZD28,新型BSP-MS/ROP控释水凝胶调控Keap1-Nrf2信号通路促进创伤性周围神经损伤后再生的作用及机制研究,2024-01至2026-12,100万,在研,主持
上海卫生健康委员会,卫生行业临床研究专项面上项目,202040257,超声引导T2胸椎旁阻滞对老年肱骨近端骨折内固定术麻醉效果的改善作用:前瞻性、随机、对照临床研究,2021-01 至 2023-12,10万,主持
国家自然基金面上项目,8157050283,miR-9 靶向TGFBR2 诱导小胶质细胞极化失衡在术后认知功能障中的作用及金刚烷胺的干预新机制研究,2016-01 至 2019-12,直接经费 57 万,主持
上海交通大学,重大疾病诊断和治疗的医工交叉研究面上项目,YG2015MS15,基于UPLC-QTOFMS的糖尿病大鼠术后认知功能障碍及金刚烷胺干预作用的代谢组学研究,2016-01 至 2018-12,21万,主持
上海市科学技术委员会,自然科学基金面上项目,15ZR1432300,丙泊酚通过调控海马IGF-2/IGF-2R通路实现遗忘效应的机制研究,2015-01 至 2017-12,10万,主持
代表性学术论文
Gang Luo#, Xiaofeng Wang#, Yongchen Cui#, Yue Cao, Zhe Zhao*, Junfeng Zhang*(张俊峰,通讯作者). Metabolic reprogramming mediates hippocampal microglial M1 polarization in response to surgical trauma causing perioperative neurocognitive disorders. J Neuroinflammation 2021; 18(1):267-282.(Q1区,IF: 9.587)
Yongchen Cui#, Xiaofeng Wang#, Yang Xu#, Yue Cao, Gang Luo, Zhe Zhao*, Junfeng Zhang*(张俊峰,通讯作者). Ropivacaine promotes axon regeneration by regulating Nav1.8-mediated macrophage signaling after sciatic nerve injury in rats. Anesthesiology 2023;139(6):782-800.(Q1区,IF: 9. 1)
Yongchen Cui, Qinjun Chu, Xiaogao Jin, Yong Li, Kaiyuan Guo, Guangming Zhang, Zhe Zhao, Junfeng Zhang*(张俊峰,通讯作者). Inhibition of KIF5b-mediated Nav1.8 transport by ropivacaine contributes to axonal regeneration following sciatic nerve injury in rats. Neuropharmacology2024; 261:110169.(Q1区,IF: 4.6)
Wenyi Zhang, Xingyun Wang, Bing Zhang, Minjiang Yi, Yinzhong Lu, Shuyan Wang, Junfeng Zhang*(张俊峰,共同通讯作者), Guangming Zhang. Single-Cell RNA-Seq Revealed the Immune Microenvironment Reprogramming by Dexmedetomidine Treatment in Ischemic Stroke. Mol Neurobiol 2025. Online ahead of print.(Q1区,IF: 4.3)
Zhao Z, Jin X, Li Y, Wang X, Cui Y, Zhang B, Kang Y, Zhang G, Chu Q , Junfeng Zhang*(张俊峰,通讯作者). Efficacy and safety of fospropofol disodium sedation for same-day bidirectional endoscopy in elderly patients: protocol for a prospective, single-center, randomized, double-blind, non-inferiority trial. FrontPharmacol 2024;15:1378081.(Q1区,IF: 4.4)
Xiaogao Jin#, Qinjun Chu#, Hailong Bing#, Fang Li, Jingyue Bai, Junge Lou, Liwei Sun, Chenxi Zhang, Lin Lin, Liumei Li, Haibo Wang, Zhanfeng Zhou, Junfeng Zhang*(张俊峰,共同通讯作者), Hongkai Lian*. Preperitoneal pelvic balloon tamponade-an effective intervention to control pelvic injury hemorrhage in a swine model. Front Bioeng Biotechnol. 2024;12:1340765.(Q1区,IF:4. 3)
Junfeng Zhang#(张俊峰), Hongyin Tan,Wei Jiang, Zhiyi Zuo*. Amantadine alleviates postoperative cognitive dysfunction possibly by increasing glial cell line-derived neurotrophic factor in rats. Anesthesiology 2014; 121(4):773-785.(Q1区,IF:5.879)
Junfeng Zhang#(张俊峰), Wei Jiang*,Zhiyi Zuo*. Pyrrolidine dithiocarbamate attenuates surgery-induced neuroinflammation and cognitive dysfunction possibly via inhibition of nuclear factor κB. Neuroscience 2014; 261(3):1-10.(IF:3.357)
Zhang J#(张俊峰), Tan H#, Jiang W*, Zuo Z*. The Choice of General Anesthetics May Not Affect Neuroinflammation and Impairment of Learning and Memory After Surgery in Elderly Rats. J Neuroimmune Pharmacol 2015; 10(1): 179-189.(IF:3.896)
崔永晨#,罗钢,曹越,张俊峰*(通讯作者)。罗哌卡因局部神经阻滞在大鼠周围神经再生中的实验研究。中华手外科杂志 2021; 37(06):468-473。
罗钢#,崔永晨,曹越,张俊峰*(通讯作者)。手术创伤对2型糖尿病小鼠术后认知功能障碍和脑葡萄糖代谢的影响。上海交通大学学报(医学版) 2020; 40(11):1468-1472。
Xiaofeng Wang, Hui Zhang, Yongzhu Chen, Zhenwei Xie, Moxi Chen Yonglin Chen, Junfeng Zhang*(张俊峰,通讯作者). The anesthetic efficacy of ultrasound-guided lumbar plexus combined with quadratus lumborum block with Shamrock approach in total hip arthroplasty: study protocol for a randomized controlled trial.Trials 2023;24(1):596.
Yue Cao#, Yongchen Cui, Junling Liao, Zhe Zhao*, Junfeng Zhang*(张俊峰,通讯作者).Sevoflurane preconditioning increases stress resistance via IMB-2/DAF-16 in C. elegans. Dose-response 2022; 20(1): 15593258221082886.
Xiaofeng Wang#, Hui Zhang, Yongzhu Chen, Qingfu, Zhang, Zhenwei Xie, Junling Liao, Wei Jiang, Junfeng Zhang*(张俊峰,通讯作者). Is It Useful and Necessary to Add a T2 Paravertebral Block to the Regional Anesthesia During Proximal Humeral Fracture Surgery in Elderly Patients? A Prospective and Randomized Controlled Trial. Front Surg 2022; 9:755298.
Jun Cao#, Xiaoyun Gao, Xiaoli Zhang, Jing Li, Junfeng Zhang*(张俊峰,通讯作者). Feasibility of laryngeal mask anesthesia combined with nerve block in adult patients undergoing internal fixation of rib fractures: a prospective observational study. BMC Anesthesiol 2020;20(1):170.
Junfeng Zhang#(张俊峰), Xiaofeng Wang#, Hui Zhang, Zhuolin Shu, Wei Jiang*. Comparison of Combined Lumbar and Sacral Plexus Block With Sedation Versus General Anaesthesia on Postoperative Outcomes in Elderly Patients Undergoing Hip Fracture Surgery (CLSB-HIPELD): Study Protocol for a Prospective, Multicentre, Randomised Controlled Trial. BMJ Open 2019; 9 (3): e022898.
Xiaofeng Wang#, Hui Zhang, Zhenwei Xie, Qingfu Zhang, Wei Jiang, Junfeng Zhang*(张俊峰,通讯作者). The Effectiveness of Additional Thoracic Paravertebral Block in Improving the Anesthetic Effects of Regional Anesthesia for Proximal Humeral Fracture Surgery in Elderly Patients: Study Protocol for a Randomized Controlled Trial. Trials 2020; 21 (1): 204-212.
邮箱:zhangjunfeng@sjtu.edu.cn